General research interest: three main axes.
- snoRNA and Ovarian Cancer: We explore the role of small nucleolar RNAs (snoRNAs) in ovarian cancer, focusing on their effects on ribosomal RNA modifications and their potential as biomarkers or therapeutic targets.
- Intron Functions and Splicing: Our research investigates the functional importance of introns in gene regulation and their involvement in fundamental cancer-related pathways, such as nutrient sensing and cellular adaptation to stress and starvation.
- Ribosome Function and Heterogeneity: We study how variations in intronic sequences, splicing, and amino acid sequence influence ribosome production and composition. Using yeast as a model system, we examine how these variations define translation patterns under different growth conditions and link them to fundamental processes in cancer biology.