2023

Bergeron D, Faucher-Giguère L, Emmerichs AK, Choquet K, Song KS, Deschamps-Francoeur G, Fafard-Couture É, Rivera A, Couture S, Churchman LS, Heyd F, Abou Elela S, Scott MS., Intronic small nucleolar RNAs regulate host gene splicing through base pairing with their adjacent intronic sequences, (2023), Genome Biol, 10.1186/s13059-023-03002-y

Bergeron D, Paraqindes H, Fafard-Couture É, Deschamps-Francoeur G, Faucher-Giguère L, Bouchard-Bourelle P, Abou Elela S, Catez F, Marcel V, Scott MS., snoDB 2.0: an enhanced interactive database, specializing in human snoRNAs, (2023), Nucleic Acids Res, 10.1093/nar/gkac835

2022

Kerkhofs K, Garg J, Fafard-Couture É, Abou Elela S, Scott MS, Pearlman RE, Bayfield MA., Altered tRNA processing is linked to a distinct and unusual La protein in Tetrahymena thermophila, (2022), Nat Commun, 10.1038/s41467-022-34796-3

Deschamps-Francoeur G, Couture S, Abou-Elela S, Scott MS., The snoGloBe interaction predictor reveals a broad spectrum of C/D snoRNA RNA targets, (2022), Nucleic Acids Res, 10.1093/nar/gkac475

Zhou D, Tran Y, Abou Elela S, Scott MS., SAPFIR: A webserver for the identification of alternative protein features, (2022), BMC Bioinformatics, 10.1186/s12859-022-04804-w

Faucher-Giguère L, Roy A, Deschamps-Francoeur G, Couture S, Nottingham RM, Lambowitz AM, Scott MS, Abou Elela S., High-grade ovarian cancer associated H/ACA snoRNAs promote cancer cell proliferation and survival, (2022), NAR Cancer, 10.1093/narcan/zcab050

Boudreault S, Martineau CA, Faucher-Giguère L, Abou-Elela S, Lemay G, Bisaillon M., Reovirus μ2 Protein Impairs Translation to Reduce U5 snRNP Protein Levels, (2022), Int J Mol Sci, 10.3390/ijms24010727

Malik Ghulam M, Catala M, Reulet G, Scott MS, Abou Elela S., Duplicated ribosomal protein paralogs promote alternative translation and drug resistance, (2022), Nat Commun, 10.1038/s41467-022-32717-y

2021

Petibon C, Malik Ghulam M, Catala M, Abou Elela S., Regulation of ribosomal protein genes: An ordered anarchy, (2021), Wiley Interdiscip Rev RNA, 10.1002/wrna.1632

Fafard-Couture É, Bergeron D, Couture S, Abou-Elela S, Scott MS., Annotation of snoRNA abundance across human tissues reveals complex snoRNA-host gene relationships, (2021), Genome Biol, 10.1186/s13059-021-02391-2

Zhou D, Couture S, Scott MS, Abou Elela S., RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners, (2021), Nucleic Acids Res, 10.1093/nar/gkab595

2020

Boivin V, Reulet G, Boisvert O, Couture S, Elela SA, Scott MS., Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA, (2020), Nucleic Acids Res, 10.1093/nar/gkaa028

Bouchard-Bourelle P, Desjardins-Henri C, Mathurin-St-Pierre D, Deschamps-Francoeur G, Fafard-Couture É, Garant JM, Elela SA, Scott MS., snoDB: an interactive database of human snoRNA sequences, abundance and interactions, (2020), Nucleic Acids Res, 10.1093/nar/gkz884

Ghulam MM, Catala M, Abou Elela S., Differential expression of duplicated ribosomal protein genes modifies ribosome composition in response to stress, (2020), Nucleic Acids Res, 10.1093/nar/gkz1183

2019

Abou Elela S, Ji X., Structure and function of Rnt1p: An alternative to RNAi for targeted RNA degradation, (2019), Wiley Interdiscip Rev RNA, 10.1002/wrna.1521

Catala M, Abou Elela S., Promoter-dependent nuclear RNA degradation ensures cell cycle-specific gene expression, (2019), Commun Biol, 10.1038/s42003-019-0441-3

Boivin V, Faucher-Giguère L, Scott M, Abou-Elela S., The cellular landscape of mid-size noncoding RNA, (2019), Wiley Interdiscip Rev RNA, 10.1002/wrna.1530

Parenteau J, Maignon L, Berthoumieux M, Catala M, Gagnon V, Abou Elela S., Introns are mediators of cell response to starvation, (2019), Nature, 10.1038/s41586-018-0859-7

Deschamps-Francoeur G, Boivin V, Abou Elela S, Scott MS., CoCo: RNA-seq read assignment correction for nested genes and multimapped reads, (2019), Bioinformatics, 10.1093/bioinformatics/btz433

Parenteau J, Abou Elela S., Introns: Good Day Junk Is Bad Day Treasure, (2019), Trends Genet, 10.1016/j.tig.2019.09.010

2018

Boivin V, Deschamps-Francoeur G, Couture S, Nottingham RM, Bouchard-Bourelle P, Lambowitz AM, Scott MS, Abou-Elela S., Simultaneous sequencing of coding and noncoding RNA reveals a human transcriptome dominated by a small number of highly expressed noncoding genes, (2018), RNA, 10.1261/rna.064493.117

2016

Comeau MA, Lafontaine DA, Abou Elela S., The catalytic efficiency of yeast ribonuclease III depends on substrate specific product release rate, (2016), Nucleic Acids Res, 10.1093/nar/gkw507

Petibon C, Parenteau J, Catala M, Elela SA., Introns regulate the production of ribosomal proteins by modulating splicing of duplicated ribosomal protein genes, (2016), Nucleic Acids Res, 10.1093/nar/gkw140

2015

Madgwick A, Fort P, Hanson PS, Thibault P, Gaudreau MC, Lutfalla G, Möröy T, Abou Elela S, Chaudhry B, Elliott DJ, Morris CM, Venables JP., Neural differentiation modulates the vertebrate brain specific splicing program, (2015), PLoS One, 10.1371/journal.pone.0125998

Gagnon J, Lavoie M, Catala M, Malenfant F, Elela SA., Transcriptome wide annotation of eukaryotic RNase III reactivity and degradation signals, (2015), PLoS Genet, 10.1371/journal.pgen.1005000

Parenteau J, Lavoie M, Catala M, Malik-Ghulam M, Gagnon J, Abou Elela S., Preservation of Gene Duplication Increases the Regulatory Spectrum of Ribosomal Protein Genes and Enhances Growth under Stress, (2015), Cell Rep, 10.1016/j.celrep.2015.11.033

2014

Deschamps-Francoeur G, Garneau D, Dupuis-Sandoval F, Roy A, Frappier M, Catala M, Couture S, Barbe-Marcoux M, Abou-Elela S, Scott MS., Identification of discrete classes of small nucleolar RNA featuring different ends and RNA binding protein dependency, (2014), Nucleic Acids Res, 10.1093/nar/gku664

Liang YH, Lavoie M, Comeau MA, Abou Elela S, Ji X., Structure of a eukaryotic RNase III postcleavage complex reveals a double-ruler mechanism for substrate selection, (2014), Mol Cell, 10.1016/j.molcel.2014.03.006

Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S., Tumor microenvironment-associated modifications of alternative splicing, (2014), RNA, 10.1261/rna.042168.113

Brosseau JP, Lucier JF, Lamarche AA, Shkreta L, Gendron D, Lapointe E, Thibault P, Paquet E, Perreault JP, Abou Elela S, Chabot B., Redirecting splicing with bifunctional oligonucleotides, (2014), Nucleic Acids Res, 10.1093/nar/gkt1287

2013

Dionne I, Larose S, Dandjinou AT, Abou Elela S, Wellinger RJ., Cell cycle-dependent transcription factors control the expression of yeast telomerase RNA, (2013), RNA, 10.1261/rna.037663.112

Venables JP, Brosseau JP, Gadea G, Klinck R, Prinos P, Beaulieu JF, Lapointe E, Durand M, Thibault P, Tremblay K, Rousset F, Tazi J, Abou Elela S, Chabot B., RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues, (2013), Mol Cell Biol, 10.1128/MCB.01174-12

Venables JP, Lapasset L, Gadea G, Fort P, Klinck R, Irimia M, Vignal E, Thibault P, Prinos P, Chabot B, Abou Elela S, Roux P, Lemaitre JM, Tazi J., MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation, (2013), Nat Commun, 10.1038/ncomms3480

Shkreta L, Bell B, Revil T, Venables JP, Prinos P, Elela SA, Chabot B., Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing, (2013), Cancer Treat Res, 10.1007/978-3-642-31659-3_3

2012

Ghazal G, Gagnon J, Elela SA., Detection and characterization of transcription termination, (2012), Methods Mol Biol, 10.1007/978-1-61779-376-9_38

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B., Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators, (2012), Mol Cell Biol, 10.1128/MCB.06130-11

Noël JF, Larose S, Abou Elela S, Wellinger RJ., Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway, (2012), Nucleic Acids Res, 10.1093/nar/gks200

Lavoie M, Ge D, Abou Elela S., Regulation of conditional gene expression by coupled transcription repression and RNA degradation, (2012), Nucleic Acids Res, 10.1093/nar/gkr759

Catala M, Aksouh L, Abou Elela S., RNA-dependent regulation of the cell wall stress response, (2012), Nucleic Acids Res, 10.1093/nar/gks411

Lund N, Milev MP, Wong R, Sanmuganantham T, Woolaway K, Chabot B, Abou Elela S, Mouland AJ, Cochrane A., Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression, (2012), Nucleic Acids Res, 10.1093/nar/gkr1238

2011

Parenteau J, Durand M, Morin G, Gagnon J, Lucier JF, Wellinger RJ, Chabot B, Elela SA., Introns within ribosomal protein genes regulate the production and function of yeast ribosomes, (2011), Cell, 10.1016/j.cell.2011.08.044

Meaux S, Lavoie M, Gagnon J, Abou Elela S, van Hoof A., Reporter mRNAs cleaved by Rnt1p are exported and degraded in the cytoplasm, (2011), Nucleic Acids Res, 10.1093/nar/gkr627

Tanackovic G, Ransijn A, Thibault P, Abou Elela S, Klinck R, Berson EL, Chabot B, Rivolta C., PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa, (2011), Hum Mol Genet, 10.1093/hmg/ddr094

Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Elela SA., Alternative splicing of SYK regulates mitosis and cell survival, (2011), Nat Struct Mol Biol, 10.1038/nsmb.2040

2010

Brosseau JP, Lucier JF, Lapointe E, Durand M, Gendron D, Gervais-Bird J, Tremblay K, Perreault JP, Elela SA., High-throughput quantification of splicing isoforms, (2010), RNA, 10.1261/rna.1877010

Bergeron L Jr, Perreault JP, Abou Elela S., Short RNA duplexes guide sequence-dependent cleavage by human Dicer, (2010), RNA, 10.1261/rna.2346510

2009

Ghazal G, Gagnon J, Jacques PE, Landry JR, Robert F, Elela SA., Yeast RNase III triggers polyadenylation-independent transcription termination, (2009), Mol Cell, 10.1016/j.molcel.2009.07.029

Venables JP, Klinck R, Koh C, Gervais-Bird J, Bramard A, Inkel L, Durand M, Couture S, Froehlich U, Lapointe E, Lucier JF, Thibault P, Rancourt C, Tremblay K, Prinos P, Chabot B, Elela SA., Cancer-associated regulation of alternative splicing, (2009), Nat Struct Mol Biol, 10.1038/nsmb.1608

Alló M, Buggiano V, Fededa JP, Petrillo E, Schor I, de la Mata M, Agirre E, Plass M, Eyras E, Elela SA, Klinck R, Chabot B, Kornblihtt AR., Control of alternative splicing through siRNA-mediated transcriptional gene silencing, (2009), Nat Struct Mol Biol, 10.1038/nsmb.1620

2008

Venables JP, Koh CS, Froehlich U, Lapointe E, Couture S, Inkel L, Bramard A, Paquet ER, Watier V, Durand M, Lucier JF, Gervais-Bird J, Tremblay K, Prinos P, Klinck R, Elela SA, Chabot B., Multiple and specific mRNA processing targets for the major human hnRNP proteins, (2008), Mol Cell Biol, 10.1128/MCB.00726-08

Venables JP, Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Koh C, Gervais-Bird J, Lapointe E, Froehlich U, Durand M, Gendron D, Brosseau JP, Thibault P, Lucier JF, Tremblay K, Prinos P, Wellinger RJ, Chabot B, Rancourt C, Elela SA., Identification of alternative splicing markers for breast cancer, (2008), Cancer Res, 10.1158/0008-5472.CAN-08-1769

Parenteau J, Durand M, Véronneau S, Lacombe AA, Morin G, Guérin V, Cecez B, Gervais-Bird J, Koh CS, Brunelle D, Wellinger RJ, Chabot B, Abou Elela S., Deletion of many yeast introns reveals a minority of genes that require splicing for function, (2008), Mol Biol Cell, 10.1091/mbc.e07-12-1254

Hai Y, Cao W, Liu G, Hong SP, Elela SA, Klinck R, Chu J, Xie J., A G-tract element in apoptotic agents-induced alternative splicing, (2008), Nucleic Acids Res, 10.1093/nar/gkn207

Shkreta L, Froehlich U, Paquet ER, Toutant J, Elela SA, Chabot B., Anticancer drugs affect the alternative splicing of Bcl-x and other human apoptotic genes, (2008), Mol Cancer Ther, 10.1158/1535-7163.MCT-08-0192

Catala M, Tremblay M, Samson E, Conconi A, Abou Elela S., Deletion of Rnt1p alters the proportion of open versus closed rRNA gene repeats in yeast, (2008), Mol Cell Biol, 10.1128/MCB.01805-07

Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Gervais-Bird J, Madden R, Paquet ER, Koh C, Venables JP, Prinos P, Jilaveanu-Pelmus M, Wellinger R, Rancourt C, Chabot B, Abou Elela S., Multiple alternative splicing markers for ovarian cancer, (2008), Cancer Res, 10.1158/0008-5472.CAN-07-2580

Lavoie M, Abou Elela S., Yeast ribonuclease III uses a network of multiple hydrogen bonds for RNA binding and cleavage, (2008), Biochemistry, 10.1021/bi800238u

2007

Lamontagne B, Abou Elela S., Short RNA guides cleavage by eukaryotic RNase III, (2007), PLoS One, 10.1371/journal.pone.0000472

Zhuo D, Madden R, Elela SA, Chabot B., Modern origin of numerous alternatively spliced human introns from tandem arrays, (2007), Proc Natl Acad Sci U S A, 10.1073/pnas.0604777104

Larose S, Laterreur N, Ghazal G, Gagnon J, Wellinger RJ, Elela SA., RNase III-dependent regulation of yeast telomerase, (2007), J Biol Chem, 10.1074/jbc.M607145200

2006

Ghazal G, Elela SA., Characterization of the reactivity determinants of a novel hairpin substrate of yeast RNase III, (2006), J Mol Biol, 10.1016/j.jmb.2006.08.028

Gaudin C, Ghazal G, Yoshizawa S, Elela SA, Fourmy D., Structure of an AAGU tetraloop and its contribution to substrate selection by yeast RNase III, (2006), J Mol Biol, 10.1016/j.jmb.2006.08.029

Lucier JF, Bergeron LJ, Brière FP, Ouellette R, Elela SA, Perreault JP., RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes, (2006), BMC Bioinformatics, 10.1186/1471-2105-7-480

Toussaint M, Levasseur G, Gervais-Bird J, Wellinger RJ, Elela SA, Conconi A., A high-throughput method to measure the sensitivity of yeast cells to genotoxic agents in liquid cultures, (2006), Mutat Res, 10.1016/j.mrgentox.2006.03.006

Gendron D, Carriero S, Garneau D, Villemaire J, Klinck R, Elela SA, Damha MJ, Chabot B., Modulation of 5′ splice site selection using tailed oligonucleotides carrying splicing signals, (2006), BMC Biotechnol, 10.1186/1472-6750-6-5

2005

Ge D, Lamontagne B, Elela SA., RNase III-mediated silencing of a glucose-dependent repressor in yeast, (2005), Curr Biol, 10.1016/j.cub.2004.12.001

Parenteau J, Klinck R, Good L, Langel U, Wellinger RJ, Elela SA., Free uptake of cell-penetrating peptides by fission yeast, (2005), FEBS Lett, 10.1016/j.febslet.2005.07.064

Ghazal G, Ge D, Gervais-Bird J, Gagnon J, Abou Elela S., Genome-wide prediction and analysis of yeast RNase III-dependent snoRNA processing signals, (2005), Mol Cell Biol, 10.1128/MCB.25.8.2981-2994.2005

2004

Dandjinou AT, Lévesque N, Larose S, Lucier JF, Abou Elela S, Wellinger RJ., A phylogenetically based secondary structure for the yeast telomerase RNA, (2004), Curr Biol, 10.1016/j.cub.2004.05.054

Catala M, Lamontagne B, Larose S, Ghazal G, Elela SA., Cell cycle-dependent nuclear localization of yeast RNase III is required for efficient cell division, (2004), Mol Biol Cell, 10.1091/mbc.e04-03-0183

Lamontagne B, Elela SA., Evaluation of the RNA determinants for bacterial and yeast RNase III binding and cleavage, (2004), J Biol Chem, 10.1074/jbc.M309324200

Faber AW, Vos JC, Vos HR, Ghazal G, Elela SA, Raué HA., The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA, (2004), RNA, 10.1261/rna.7155904

Lamontagne B, Hannoush RN, Damha MJ, Abou Elela S., Molecular requirements for duplex recognition and cleavage by eukaryotic RNase III: discovery of an RNA-dependent DNA cleavage activity of yeast Rnt1p, (2004), J Mol Biol, 10.1016/j.jmb.2004.02.059

2003

Villemaire J, Dion I, Elela SA, Chabot B., Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides, (2003), J Biol Chem, 10.1074/jbc.M308897200

Lamontagne B, Ghazal G, Lebars I, Yoshizawa S, Fourmy D, Elela SA., Sequence dependence of substrate recognition and cleavage by yeast RNase III, (2003), J Mol Biol, 10.1016/s0022-2836(03)00231-6

2002

Tremblay A, Lamontagne B, Catala M, Yam Y, Larose S, Good L, Elela SA., A physical interaction between Gar1p and Rnt1pi is required for the nuclear import of H/ACA small nucleolar RNA-associated proteins, (2002), Mol Cell Biol, 10.1128/MCB.22.13.4792-4802.2002